FACILE SYNTHESIS AND CHARACTERIZATION OF A BROMINE-SUBSTITUTED (CHLOROMETHYL)PYRIDINE PRECURSOR TOWARDS THE IMMOBILIZATION OF BIOMIMETIC METAL ION CHELATES ON FUNCTIONALIZED CARBONS

Facile Synthesis and Characterization of a Bromine-Substituted (Chloromethyl)Pyridine Precursor towards the Immobilization of Biomimetic Metal Ion Chelates on Functionalized Carbons

Multidentate ligands involving tethered WATERMELON pyridyl groups coordinated to transition metal ions have been frequently used to mimic the 3-histidine (3H), 2-histidine-1-carboxylate (2H1C) brace motifs or other combinations of histidine and carboxylate endogenous ligating residues found in bioinorganic metalloenzymes.It is of interest to immobi

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Challenging biliary strictures: pathophysiological features, differential diagnosis, diagnostic algorithms, and new clinically relevant biomarkers - part 1

It is frequently challenging to make the correct diagnosis in patients with biliary strictures.This is particularly important as errors may have disastrous consequences.Benign-appearing strictures treated with stents may later be revealed to be malignant MEMORY CARE and unnecessary surgery for benign strictures carries a high morbidity rate.In the

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Mechanistic and therapeutic distinctions between cardiosphere-derived cell and mesenchymal stem cell extracellular vesicle non-coding RNA

Abstract Cell therapy limits ischemic injury following myocardial infarction (MI) by preventing cell death, modulating the immune response, and promoting tissue regeneration.The therapeutic efficacy of cardiosphere-derived cells (CDCs) and mesenchymal stem cells (MSCs) is associated with extracellular vesicle (EV) release.Prior head-to-head compari

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